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(MedicalNewsToday April 2010) – Australian scientists were able to demonstrate that even a little weight loss can reverse damaging effects seen in the immune cells of obese and overweight people.

From Sydney’s Garvan Institute of Medical Research, Dr. Alex Viardot and Associate Professor Katherine Samaras found the results showing how the immune system is weakened by fat. There was an 80% reduction of the pro-inflammatory T-helper cells and the reduced activation of other immune cells circulating around the body. This study has been published at the prestigious Journal of Clinical Endocrinology Metabolism; results of which are also published online.

The immune system needs all the cells to properly function to protect the body from germs, microbes, and other invaders. These all need to exist in a determined balance to function properly and to protect Excess body fat can well tip off this sensitive balance and cause the immune system to create cells to attack rather than to protect.

It has been shown that abdominal fat primarily accounts for the production of pro-inflammatory cells that does all the damage.

Associate Professor Samaras notes further, “Obesity is one of the major causes of Type 2 diabetes including some cancers, where excess weight disorders affect about 50% of adult Australians. This situation already reached to crisis levels, and the general public must be informed that since excess fat promotes the growth of inflammatory cells that harbor a lot of serious illnesses, it affects the immune system, it also affects their survival.”

“Lose weight of about 6kg and the immune cells that protect will go back. It has been shown for the first time that the very adverse effects of inflammatory cells are reversed with weight loss.” Samaras concludes.

Category : News

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